The Kafue Lechwe (Kobus leche kafuensis) is an ungulate (hoofed) mammal in the antelope family of waterbucks. It is a sub-species of the Southern Lechwe.

The Kafue Lechwe has golden-brown fur with a white underbelly. The male is darker than the female. The male has long, spiral horns, similar in shape to a lyre musical instrument. The female does not have horns. Its hind (back) legs are longer than other antelope legs. It is adapted to long-distance running. It has large ears with black markings.